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Case Number 106026 - Molecular Profiling of Thyroid Cancer

Description:  This invention provides methods for characterizing thyroid tissue by detecting the gene expression levels for certain genes, such as kallikrein 10 and claudin 1, among others. This provides a novel approach for detecting thyroid carcinomas by detecting altered gene expressions in thyroid tissue samples (relative to expression levels in normal thyroid tissues). Furthermore, the level of specific gene expression can be used to discriminate between the different types of thyroid cancer e.g., papillary versus follicular.

A patent on expressed profile of thyroid cancer (7,598,052) has been issued and another is pending.

For a more detailed description of the invention see University of Michigan's Tech Finder Website

For more information please contact Kellen Sensor at 513-558-5621 or

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