Case Number 106013 - Software for the Resolution of Sequence Information from Affymetrix Gene Chip

Contact: Geoffrey Pinski
Email: pinskig@ucmail.uc.edu
Phone: 513-558-5696

Description:  What the invention does is to confer the ability to read sequence data from Affymetrix custom or standard re-sequencing chips. It increases the efficiency from about 95% efficiency up to above 99% efficiency, so this software and this algorithm represents a method to have much higher confidence and more useful data than could be generated from these single chip assays to be used for individual patient analysis. The algorithm represents a very valuable advancement to the use of the sequencing chips, and therefore, constitutes an important invention for improved use of this technology. The ability to use these chips in a clinical situation is thus greatly improved by the use of this new algorithm that we have developed in the Division of Biomedical Informatics at Cincinnati Children's Hospital. The new algorithm and program can work itself or it can be incorporated into the existing Affymetrix software.